Effective Antiepileptic Raws Phenytoin sodium Powder

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Description

Simple introductions of Phenytoin sodium Powder
Product Name:Phenytoin Sodium
CAS Number:630-93-3
Product Purity:99.66%
Appearance: white crystalline Powder
Molecular formula: C15H11N2NaO2
Molecular weight:274.25
Density‎: ‎1.3±0.1g/cm3
Boiling Point‎: ‎464.0±55.0℃ at 760 mmHg
Melting Point: 290-299℃
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What are the applications of Phenytoin Sodium Powder?
Phenytoin sodium has a highly selective inhibitory effect on the cerebral cortex motor area and is generally thought to stabilize the brain cell membrane and increase the brain’s inhibitory neurotransmitters serotonin (5-HT) and gamma-aminobutyric acid. (GABA) acts to prevent the spread of abnormal discharge and has an anti-epileptic effect.
The mechanism of action against neuropathic pain may be related to the action of this product with the central nervous system, reducing synaptic transmission or reducing transient stimuli that cause neuronal firing.
It can also inhibit the ectopic rhythm of the atria and ventricles, accelerate the conduction of the atrioventricular, reduce myocardial self-discipline, and have anti-arrhythmia effects.

What are the dosages and cycles of Phenytoin sodium?
Antiepileptic: oral, adult, 100mg/ time, 2-3 times/day,
Take it after meals, gradually increase to 600mg/ day after a few days, and maintain the dosage after stabilization.
Children, 5mg/kg/day, Max. 300mg/ day, maintenance dosage: 4mg~8mg/kg,
For children over 6 years old, it can be used for adults.Anti-arrhythmia: commonly used in adults:
100~300mg, one dose or two to three doses, or 10~15mg/kg on the first day,
On the 2nd ~ 4th day, 7.5~10mg/kg, maintenance dosage 2~6mg/kg.
Usual dosage for children: start according to body weight 5mg/kg,
Oral administration is divided into 2 to 3 times, and the daily dose should not exceed 300mg according to the patient’s condition.
Maintenance dosage: 4~8mg/kg, or 250mg/m2 according to the body surface area, in 2-3 oral doses.