Quick details of Andarine(S-4)
Product Name: Andarine(S-4)
Synonyms: S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide;N-[4-Nitro-3-(trifluoromethyl)phenyl]-(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methylpropanamide;Ostarine;(2R)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide;MK-2866;Andarine;Propanamide,3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phe nyl]-,(2S)-;SARMs S-4
Appearance: White powder
Packing: Stealth pack
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What is Andarine(S-4)?
As a research chemical, S-4 belongs to a class of chemicals known as SARMS or selective androgen receptor modulators. Like typical androgens, SARMS bind to the androgen receptor however SARMS create selective anabolic activity.
Compared to testosterone and other anabolic steroids and pro hormones, the advantage of SARMS such as S-4 is that they do not have androgenic activity in non-skeletal-muscle tissues.
S4 was designed for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the non-steroidal androgen antagonist bicalutamide as a lead compound.
As an orally active partial agonist for androgen receptors, S-4 is effective in not only maintaining lean body mass but actually increasing it.
HOW IT WORKS
All SARMs work by binding to the androgen receptors, which results in anabolic activity. Furthermore, there is more
protein synthesized, allowing more muscle to be created. These effects are similar to those seen with anabolic
steroids. However, in the case of SARMS, there is no aromatization, liver strain, severe HPTA (hypothalamic pituitary
testicular axis) suppression and general side effects.
STACKING for Andarine(S-4)
Andarine can be used by itself, but it works even better when stacked because different drugs and compounds will work in synergy. There are a few ways to stack andarine, which I will illustrate below. All milligram (mg) examples are
daily dosages, and you can run andarine for up to 12 weeks at a time.
1.Endurance: you can stack andarine at a low dose with cardarine (GW 501516) at 20mg per day for an increase in endurance.
2.Fat loss: the best shredder stack would be the combination of 20mg of cardarine with 50-75mg of andarine. This combination is well known as a potent ‘cutting’ stack.
3.Anabolic steroid stack: Stacking andarine as part of an anabolic steroid cycle is a good way to help increase strength and lean muscle mass without giving additional side effects to your cycle.
4.As a stand alone: Andarine used by itself at 50-75mg. It is, in my opinion, one of the best SARM’s for increasing strength quickly. You will be moving more weight within 1-2 weeks, and the side effects will be minimal.
5.SARMs triple stack: If you want to recomp, andarine stacks beautifully with cardarine and ostarine (MK 2866).
SIDE EFFECTS of Andarine(S-4)
Andarine does not aromatize, it is not suppressive when used properly, and it will not harm the liver.
However, andarine is known for one side effect – its affinity to bind to the androgen receptors in the eyes, which is not permanent or harmful. When this happens, the user may have problems adjusting their vision from darkness to light, or they will notice a yellow tint. If this becomes a problem, you can lower the dose down or take a couple days off from taking it. Therefore, there is nothing to worry about because once the compound is stopped, your vision will return to normal within a few days to a week.
The half life of andarine is only 4-6 hours.
Andarine(S-4) Dosing for cutting
A 50mg dosing protocol for 6-8 weeks is ideal for cutting purposes for the majority of users.
However due to the vision side effects, if running at these doses some like to follow a 5 on 2 off protocol where S4 is used for 5 days followed by a 2 day break (then this cycle is repeated).
DOSAGE AND USE
The typical dosage is 50-75mg total per day, taken in the morning and in the evening in split dosages. In liquid form you are to carefully drop the liquid into the mouth and swallow (do not hold under tongue), and then chase it down with some juice or water; besides, do not mix the liquid into a cup with juice because it can sink or stick to the cup and be lost.
Uses of S-4 for Losing Body fat
Cutting is the environment where S-4 truly shines.
Certain steroids are considered “cutting” steroids such as Winstrol and Anavar. These steroids don’t offer too much in large gains in muscle mass but are very effective in leaning out the body. The SARM S-4 has very similar properties.
The presence of androgen receptors in human preadipocytes and adipocytes suggests that androgens may contribute, through regulation of their own receptors, to the control of adipose tissue development. As S-4 shows this binding affinity to the AR, it demonstrates the similar fat burning effects. S-4 also shows a decrease in LPL (lipoprotein lipase) which is an enzyme that causes lipid accumulation.
S-4 also fits into a cutting protocol for the concurrent reduction in body fat with maintenance of muscle mass in a hypocaloric environment.
One of the most disheartening outcomes of cutting is the loss hard earned muscle mass. The drop in metabolic rate and hormone levels (T3, IGF, Testosterone etc) with the lack of calories is a perfect catabolic environment for loss of muscle tissue.
As S4 has both anabolic and androgenic effects in muscle tissue, it will not only help with fat loss, but maintain and even increase muscle mass when cutting.
S-4 causes increases in vascularity and promote a very nice, “quality”, hard look to the users muscles, with little or no water retention.
In this way S-4 can be compared to Winstrol, without the harsh hair loss or extreme adverse effects on cholesterol.
Also other popular steroids/Prohormones used for cutting such as winstrol or epistane can have a notable effect on drying out of the joints. S-4 doesn’t suffer such consequences so the athlete is still able to lift heavy in order to maintain/increase muscle mass and strength.
Another advantage S-4 offers for cutting is that it doesn’t give the painful pumps associated with other popular steroids/Prohormones. Back and calf pumps are particularly detrimental for cutting as it limits the ability to perform cardio.