Non-steroidal Anti-inflammatory Analgesic Raws Indometacin Powder

CERTIFICATE OF ANALYSIS (INDOMETHACIN Powder)

Product name INDOMETHACIN
CAS No. 53-86-1 Outer Packing 25KG
Standard adopted BP2013
Items of analysis Specification Results
Description White or yellow crystalline powder , Pratically insoluble in water, sparingly Soluble in alcohol Complies
A. Melting point 158℃~162℃ 160℃~161℃
B: Absorption at 318nm 170~190 184
C Conforms to the requirement Conforms
D Conforms to the requirement Conforms
E Conforms to the requirement Conforms
Heavy metals ≤20ppm Pass
Related substances(TLC) ≤0.5% 0.04%
Loss on drying ≤0.5% 0.20%
Sulphated Ash ≤0.1% 0.03%
Assay 99.5~100.5% 99.70%
Any Individual Impurity ≤0.10% 0.05%
Sum of all Impurity ≤0.30% 0.20%
Conclusion Qualified

 

 

Description

Simple introductions of Indomethacin Powder
Product Name:Indomethacin
Alias: indometacin
CAS Number:53-86-1
Product Purity:99.70%
Appearance: White or yellow crystalline powder , Pratically insoluble in water, sparingly Soluble in alcohol;
Molecular formula:C19H16ClNO4
Molecular weight: 357.79g/mol
Boiling Point‎: ‎499.4±45.0℃ at 760 mmHg
Density‎: ‎1.3±0.1g/cm
Index of Refraction‎: ‎1.619
Melting point:159.9–163.2℃
Flash point:255.8℃
Vapor pressure:8.61E-11mmHg at 25℃
Usages: Indomethacin is used to relieve pain, swelling, and joint stiffness caused by arthritis, gout, bursitis, and tendonitis. It is also used to relieve pain from various other conditions. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).
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Product attributes:Antipyretic and analgesic non-steroidal anti-inflammatory drugs;
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What are the applications of Indomethacin?
Indomethacin has obvious effect on relieving inflammatory pain.

It is used in acute and chronic rheumatoid arthritis, gouty arthritis and cancer pain.

It can also be used to treat bursitis, tenosynovitis and arthritis.

What are dosages of Indomethacin?
1.Normal adult dosage:
(1) anti-rheumatism, the initial dose of 25 ~ 50mg once, 2 ~ 3 times a day, the maximum daily dose should not exceed 150mg.
(2) the first dose of 25 ~ 50mg, followed by 25mg, three times a day, until the pain relief, can be stopped;
(3) antifebrile, once 6.25 ~ 12.5mg, no more than 3 times a day.
2.Dosage for children: 1.5 ~ 2.5mg/kg per day, divided into 3~4 times.Keep to a minimum when effective.